In this presentation we will present the initial evaluation of air quality model simulations by the MPAS-CMAQ system for the full year of 2016 using a mesh with 92 km global resolution refining to 25 km over North America. Global emissions from EDGAR-HTAP are combined with the 2016 EPA National Emission Inventory for the US. Evaluation of meteorology simulated by the EPA-enhanced version of MPAS-A that includes the addition of four-dimensional data assimilation (FDDA), the ACM2 PBL model, and PX land surface model will be presented in another talk. This presentation will focus on global and US evaluations of concentrations and deposition of air quality constituents. Evaluation includes comparisons to gas and aerosol surface-based measurement networks in the US and other regions of the world. In addition, we compare to global satellite data such as MODIS AOD and OMI NO2. Our technique of assimilating ozone concentrations from GFS analyses for layers above the tropopause is evaluated through comparisons to the WOUDC global ozonesonde network.