Here we consider the effect of a temporally varying bottom friction on jet strength and spacing. We use a two-layer quasi-geostrophic (QG) model in a doubly periodic domain on a beta plane, with a rigid lid and flat topography. The model is spun up with constant β and bottom friction (κ). Once the model has equilibrated, we vary κ in two ways: (1) a step-change (increase or decrease) or (2) a linear increase or decrease. In (1), an increase in friction leads to a re-organization of the jet structure. The transition period involves a weakening of existing jets, as well as increased meandering associated with the formation of new jets. However, a subsequent decrease in bottom friction to its original value does not result in the jets returning to their original structure. Instead, the new jet structure persists and strengthens. Thus hysteresis occurs with respect to jet spacing and bottom friction. We also (2) consider a linear increase or decrease in κ, which leads to the same qualitative results. However, we can now follow the temporal evolution of jet structure changes. In the case of increasing κ, a threshold value is reached, at which point the jet structure re-organizes. We find that the jets continuously weaken (strengthen) as κ increases (decreases). Just before the jets re-organize, we see a sharp increase in eddy strength, indicating these abrupt transitions in jet structure are mediated by eddies. We discuss the role of eddy potential vorticity (PV) fluxes in facilitating these transitions through modifications in Reynolds stress divergence and the anisotropy of coherent mesoscale eddies.