During the TexAQS II campaign in summer 2006 (08/07/06 - 09/30/06) continuous online measurements of C₂ - C₁₀ Volatile Organic Compounds (VOCs) were performed with an online gas chromatograph (GC/FID) at the Moody Tower supersite on the University of Houston campus. In addition, VOC data was obtained with the TCEQ and Enhanced Industry Sponsored Monitoring auto-GC networks near the Ship Channel area. This paper reports comparative analysis of source contributions at the Moody Tower receptor site and at one site in the Ship Channel which represents major industrial emissions, with the goal of assessing the impact of Ship Channel emissions on the receptor site Moody Tower, which is located about 10 km away from the Ship Channel. The analysis of VOC results indicates complex mixtures from traffic, industrial, and biogenic sources. In order to identify and apportion these source contributions of the VOCs to the receptor site during the campaign, multivariate receptor models were applied. The results of a principal component analysis (PCA) and a positive matrix factorization (PMF) reveal a set of factors and source profiles that are associated with several anthropogenic (industrial, traffic) as well as biogenic sources.