Recent developments in satellite remote sensing of aerosols over land provide new tools for monitoring particulate matter air quality with high temporal and spatial resolution. We will present an analysis of satellite retrieved aerosol optical thickness (AOT) data over the past seven years focused primarily over the South Eastern United States (EPA region 4). We will also explore the effects on monthly, seasonal and annual means due to spatial and temporal sampling issues associated with satellite observations. Estimation of fine particulate matter mass from observed satellite aerosol optical thickness values is still under in its infancy and requires other ancillary information before a good estimation of surface PM2.5 mass can be made. Current study will explore the AOT-PM2.5 relationships over longer time periods and evaluate the capabilities of satellite data for air quality monitoring.