Monochromatic radiative signature of Asian dust was simulated in the 650–2750 cm^-1 wavenumber band with a 0.25 cm^-1 resolution. To solve the radiative transfer equation with the absorption and scattering by mineral dust, the Successive-Order-of-Interaction (SOI) radiative transfer model was used. Simulation was done for various aerosol optical depths and dust altitudes using optical properties of mineral dust, which were obtained from mineral transported model of the Optical Properties of Aerosols and Clouds (OPAC) database. The OPAC data were updated with the size distribution retrieved from ten years of sky radiometer measurements at Dunhuang, China, which is located at the eastern edge of Taklamakan desert. Results indicate that the effect of mineral dust on IR brightness temperature appears significant in the window regions by considering that brightness temperature between clear and dusty conditions are up to 11 K with aerosol optical depth of 2.5 and dust altitude of 2.4 km. The results will be used for developing the dust retrieval algorithm from hyperspectral images from sensors such as Infrared Atmospheric Sounding Interferometer (IASI).