This paper will compare the use of quality controlled rain gauge data from the South Florida Water Management District (SFWMD) with the gridded FSU MPE dataset in the MIKE SHE hydrologic model. Both hourly and daily time steps will be examined. MIKE SHE is a fully integrated and distributed, physically based mathematical model that describes the flow within the entire land-based phase of the hydrological cycle. Our paper will consider the 1661 km2 Big Cypress Basin (BCB) in southern Florida. The basin is very flat, with an elevation difference of ~ 12 m over the entire domain. Stage heights from the model will be evaluated against observed daily stage heights provided by SFWMD. Differences between gauge versus multi-sensor precipitation at daily and hourly time steps will be quantified over a three year interval (2003-2005), over seasonal periods, and over multiple case studies. In summary, this study will evaluate the potential of using spatially distributed, multi-sensor rainfall for hydrological modeling within the relatively flat terrain of SFWMD.