Here, I compare and contrast the response of the Arctic climate system to positive radiative perturbations that result from (1) orbital variations (mid-Holocene period) and (2) increased CO2. The focus is on four processes believed to generate important climatic feedbacks in the Arctic: changes in clouds, vegetation, sea ice motion, and atmospheric energy import from lower latitudes. These processes are examined with two widely used GCMs: an atmosphere/mixed-layer ocean model (GENESIS) and an atmosphere/dynamical-ocean model (Community Climate System Model (CCSM)). The results show that sea ice dynamics act as a cooling mechanism to temper the magnitude of warming in both scenarios, due to internal ice feedbacks and to atmospheric circulation changes induced by a mobile ice pack. The flux of atmospheric moist static energy into the Arctic increases under greenhouse warming (positive feedback) but decreases in the warm paleoclimate (negative feedback). Arctic cloud cover shows virtually no change in the mid-Holocene simulations, whereas cloud fraction under higher CO2 increases substantially in GENESIS but decreases slightly in CCSM. Vegetation changes appear to act as a positive feedback mechanism in both scenarios, due to the poleward expansion of low-albedo boreal forest replacing high-albedo snow cover.