We present data that has been collected during the North Atlantic and Marine Ecosystems Study (NAAMES), which is a multiple air-campaign study intended in part to better determine the relationship and seasonal cycle between marine aerosols and cloud properties. Over the North Atlantic, natural variations in marine particle sources occur as a result of seasonal changes in ecosystem properties and meteorology. Cloud properties (including: Nd and other size distribution parameters, cloud optical thickness and cloud physical thickness) are all retrieved using remote sensing data of the Research Scanning Polarimeter (RSP). Aerosol concentrations and chemical composition are measured using in situ aerosol instruments. Our results show how variations in CCN concentration and composition correlate with variations in cloud micro- and macro-physical properties. A 46% increase in CCN concentrations is observed during NAAMES-2 (spring) when compared with the NAAMES-1 (fall) campaign. A corresponding cloud seasonal cycle is seen whereby cloud droplets with large effective radii (Reff) and low Nd are observed during the fall campaign and, conversely, smaller Reff with high Nd are observed in the spring. Throughout both campaigns a correlation coefficient of 0.82 is found between Nd and CCN concentrations. As expected, a negative correlation coefficient of -0.69 is found between the mean Reff and CCN concentration. We find a weak positive correlation between cloud optical thickness and CCN concentration and also between cloud physical thickness and CCN concentration. We use aerosol chemical composition and meteorological considerations to attribute primary drivers of seasonal changes in cloud properties. With the abundance of in situ and remote sensing instruments involved, this campaign provides an excellent opportunity to study aerosol-cloud interactions.