Here, we used a regression-based approach in combination with temperature estimates from a high-resolution, gridded meteorological dataset (PRISM) to estimate the number of deaths attributable to heat in 297 counties representing 62% of the US population, 1997-2006. Specifically, we used distributed lag non-linear models with a quasi-Poisson distribution to estimate the 21-day cumulative association between daily mean temperature and all-cause mortality (excluding external causes) in each county, controlling for seasonal and long-term time trends, day of week, and federal holidays. We then used these county-specific associations to calculate the number of deaths attributable to heat in each county.
Between 1997 and 2006 a total of 12,992,584 deaths occurred in the study counties. Across all 297 counties, we estimate that an average of 5313 deaths per year (95% empirical confidence interval: 4502, 5972) are attributable to heat (defined as all temperatures greater than the location-specific minimum mortality temperature). Extreme heat (defined as temperatures greater than the 97.5th percentile of the local daily mean temperature distribution) contributed to an average of 2218 deaths per year (95% empirical confidence interval: 1985, 2379), while moderate heat (defined as temperatures between the location-specific minimum mortality temperature and the 97.5th percentile of the local daily mean temperature distribution) contributed to an average of 3094 deaths per year (95% empirical confidence interval: 2420, 3689). These results suggest that the number of heat-related deaths occurring in the United States is substantially larger than is often reported, and highlight the importance of moderately hot temperatures in driving the burden of heat-related mortality.