We present results from a wide range of reanalysis, satellite, and sounding products that examine tropical tropopause layer temperature signals induced by several key modes of variability in the tropics: the MJO, the QBO, El Niño/Southern Oscillation, and the annual cycle. Of most interest in our findings is evidence of seasonal variations and long-term trends in QBO temperature anomalies that we believe have not been discussed in the literature: QBO temperature anomalies are stronger in boreal winter than the annual mean, and stronger in recent decades. These trends have implications for the MJO-QBO link, and underscore the degree to which the tropical tropopause layer is a dynamic region of the tropical atmosphere in which many modes interact on multiple timescales. Among the questions and hypotheses our results raise are the role of feedbacks in the tropical tropopause layer, why there is a seasonality in the MJO-QBO relationship, and whether the QBO is being altered by anthropogenic climate change.