El Niño Southern Oscillation (ENSO) has been linked to climate anomalies disturbing normal patterns of air pressure, tropical rainfall and winds, leading to changes in weather around the world and controlling the seasonal variability of the precipitation in different regions. In Argentina, El Niño events were associated with enhanced likelihood of above normal precipitation during October-February while lower than normal precipitation during the same period was typical of the La Niña years. However, evidences exists that ENSO effects are different according to the regions, even inside Argentina. This paper presents an analysis of the relationship between ENSO and rainfall variability in the south region of the Province of Cordoba in Argentina. Monthly precipitations series of the period 1961-2000, from seventeen stations in the region, were correlated with the Southern Oscillation Index (SOI). Significance of the ENSO signal was evaluated along the region and the SOI potential for predicting rainfall variability was analyzed according to the planting time and to the length of the growing season for the main crops in the area.