As a case study we focus on one such neighborhood in Los Angeles. We use the ENVI-met microscale atmospheric modeling tool to assess the footprint effects of limited-area urban heat mitigation strategies, including both roof-level and ground-level albedo enhancement. Results for near-surface ambient air temperature perturbations are presented. These results are then used to drive building indoor thermal environment simulations with EnergyPlus to explore potential for targeted urban heat mitigation to improve indoor conditions during heat waves. Also, recognizing inherent modeling limitations associated with the user-friendly nature of ENVI-met, we conducted sensitivity tests and compare ENVI-met performance to results from a more sophisticated Computational Fluid Dynamics tool (Star-CCM+) for a range of neighborhood configurations and implementations of mitigation strategies. From these comparisons we conclude that ENVI-met must be used with caution for exploring roof-level heat mitigation strategies, particularly for multi-story buildings.