Two sets of doubling CO2 simulations with prescribed ozone fields were conducted: one that includes the stratospheric water vapor feedback, and the other that eliminates the feedback by fixing the stratospheric water vapor concentrations. The differences between these two simulations quantify stratospheric water vapor feedback. We find a large stratospheric water vapor feedback in GEOSCCM that reduces the climate feedback parameter by 0.12 Wm-2K-1 and increases global surface warming by nearly 20%. Additional doubling CO2 simulations with interactive ozone chemistry were conducted in order to quantify the chemical modification of stratospheric water vapor feedback. The results show that interactive ozone leads to tropical tropopause cooling and reduces stratospheric water vapor feedback by nearly 50%. Our results suggest that stratospheric water vapor and ozone feedbacks significantly contribute to climate sensitivity.