In this study, the impact of the currently available Spire GPS-RO observations on the global short-term forecast will be quantified using standard data assimilation methods, including 4DEnVar and 3DVar, over a series of data-denial experiments. Considerations for the data assimilation configuration and observation usage in this study will follow knowledge gleaned from similar previous studies that assimilated GPS-RO observations from Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) and Challenging Minisatellite Payload (CHAMP) and found that the GPS-RO information leads to forecast model bias and RMS error reduction. Those studies will guide such choices as the assimilation of bending angle vs. refractivity, quality control, observation operator, and the interaction of GPS-RO observations with other standard datasets routinely assimilated. The improvement of the forecasts in studies using GPS-RO observations from other platforms lead us to expect that the assimilation of Spire GPS-RO observations will also lead to improvement of the global short-term forecast.